Novartis Pharma Schweiz AG, Postfach, CH-3001 Bern, Tel. + 41 0 ; 377 51.
Table 7: Orphan Products for TB, Malaria, and African Sleeping Sickness Source: Tufts CSDD ; Orphan Designation Year 1985 1986 Generic Name rifampicin Rifadin IV ; rifampicin, isoniazid, prazinamide Rifater ; eflornithine hcl DFMO Ornidyl ; mefloquine hcl Mephaquin ; mefloquine hcl, Mephaquin ; aconiazide mefloquine hcl Lariam ; mefloquine hcl Lariam ; halofantrine Halfan ; aminosalicylic acid aminosidine thalidomide sodium dichloroacetate rifapentine Priftin ; artesunate Rifalazil Company Marion Merrell Dow; HMR, Aventis Marion Merrell Dow; HMR; Aventis Marion Merrell Dow; HMR; Aventis Mepha AG Switz ; Mepha AG Switz ; Lincoln Diagnostics USA ; Hoffman-La Roche USA ; Hoffman-La Roche USA ; SmithKline Beecham USA GSK Jacobus Pharmaceutical USA ; Dr. Thomas Kanyok USA ; Celgene Corporation USA ; University of Florida USA ; HMR; Aventis World Health Organization Switz. ; Pathogenesis Corp. USA ; Orphan Approval Y 1989 ; Y 1984 ; Y 1990 ; Orphan Designated Disease Indication Tuberculosis treatment where oral form is unfeasible Tuberculosis short course treatment Trypanosoma brucei gambiense infection sleeping sickness ; Prevention: Malaria falciparum chloroquine-resistant Treatment: Chloroquine-resistant falciparum Malaria Tuberculosis Prevention: Plasmodium falciparum malaria resistant to other drugs Treatment: Acute malaria due to Plasmodium falciparum & Vivax Malaria acute mild to mod due p. falciparum p.vivax Tuberculosis infections Tuberculosis Mycobacterial infections due to mycobacterium TB & nontuberculous mycobacterium Malaria caused lactic acidosis Y 1998 ; Tuberculosis pulmonary Malaria Pulmonary Tuberculosis!
Orientation Meeting for Caregivers Time: 8: 30 10: 00 a.m. Place: Chapter Office Queens Orientation Meeting for Caregivers Time: 12: 30 2: 00 p.m. Place: Samuel Field YM-YWHA Cape Conference Room, 59-28 Little Neck Parkway, Little Neck, NY Medicaid Home Care Seminar: A Practical Guide to the System Time: 5: 30 7: p.m. Place: Chapter Office NOTE: Prior attendance at a Legal Financial Seminar required.
Verapamil may increase the effect of hypertensives and the concentration of digoxin in serum. A concurrent application of verapamil and drugs having cardiopressory effect, i.e. negative effect on atrioventricular conductivity has a summarizing effect blockers, other antiarrhytmics and inhalation anesthetics ; . Quinidine, concurrently applied with verapamil, in patients suffering hyperthropic cardiomyopathy causes hypotension. Rifampicin, isoniazid and ethambutol reduce, and cyclosporine increases verapamil concentration in plasma. Verapamil increases theophylline and carbamazepine toxicity. Digoxin concentration in plasma can also be increased. Verapamil increases toxic effects of lithium. There have been interactions with antiepileptics observed: phenobarbitone increases clearance and reduces bioavailability of verapamil tablets. It also reduces its binding to plasma proteins. Phenytoin causes a significant reduction in verapamil concentration. Cimetidine can increase verapamil concentration in plasma!
A guideline on foot care has been published by the Royal College of General Practitioners in April 2000; this will be updated by NICE in 2003 04. The full guideline is available on the NICE website, nice , and on the National Electronic Library for Health's website, nelh.nhs . The guideline developers are listed in Appendix A.
Medicines value home allergies anti-depressants anti-infectives anti-psychotics anti-smoking antibiotics asthma cancer cardio & blood cholesterol diabetes epilepsy gastrointestinal hair loss herpes hiv hormonal men's health muscle relaxers other pain relief parkinson's rheumatic skin care weight loss women's health allegra atarax benadryl clarinex claritin clemastine periactin phenergan pheniramine zyrtec anafranil celexa cymbalta desyrel effexor elavil, endep luvox moclobemide pamelor paxil prozac reboxetine remeron sinequan tofranil wellbutrin zoloft albenza amantadine aralen flagyl grisactin isoniazid myambutol pyrazinamide sporanox tinidazole vermox abilify clozaril compazine flupenthixol geodon haldol lamictal lithobid loxitane mellaril risperdal seroquel nicotine zyban achromycin augmentin bactrim biaxin ceclor cefepime ceftin chloromycetin cipro, ciloxan cleocin duricef floxin, ocuflox gatifloxacin ilosone keftab levaquin minomycin noroxin omnicef omnipen-n oxytetracycline rifater rulide suprax tegopen trimox vantin vibramycin zithromax advair aerolate, theo-24 brethine, bricanyl ketotifen metaproterenol proventil, ventolin serevent singulair arimidex casodex decadron eulexin femara levothroid, synthroid nolvadex provera, cycrin ultram vepesid zofran acenocoumarol aceon adalat, procardia altace atenolol amlodipine avapro caduet calan, isoptin capoten captopril hctz cardizem cardura catapres cilexetil, atacand clonidine, hctz combipres cordarone coreg coumadin cozaar dibenzyline diovan fosinopril hydrochlorothiazide hytrin hyzaar inderal ismo, imdur isordil, sorbitrate lanoxin lasix lercanidipine lopressor lotensin lozol micardis minipress moduretic normadate norpace norvasc plavix plendil prinivil, zestril prinzide rythmol tenoretic tenormin trental valsartan hctz vaseretic vasodilan vasotec zebeta crestor lipitor lopid mevacor pravachol tricor zocor accupril actos alpha-lipoic acid amaryl avandia diamicron mr glucophage glucotrol glucotrol xl glucovance lyrica micronase orinase prandin precose starlix depakote dilantin lamictal neurontin sodium valproate tegretol topamax trileptal valparin aciphex asacol bentyl cinnarizine colospa compazine cromolyn sodium cytotec imodium motilium nexium nexium fast pepcid ac pepcid complete prevacid prilosec propulsid protonix reglan stugil zantac zelnorm zofran propecia, proscar famvir rebetol valtrex zovirax combivir duovir-n epivir pyrazinamide retrovir sustiva videx viramune zerit ziagen aldactone calciferol danocrine decadron prednisone provera, cycrin synthroid avodart flomax hytrin levitra propecia, proscar viagra lioresal soma tizanidine ibuprofen zanaflex accupril alpha-lipoic acid amantadine aralen arcalion aricept ascorbic acid benadryl bentyl betahistine calciferol carbimazole compazine cyklokapron ddavp, stimate detrol dihydroergotoxine ditropan dramamine exelon florinef imitrex imuran isoniazid lasix melatonin myambutol nimotop orap persantine piracetam pletal quinine rifampin rifater rocaltrol strattera ticlid tiotropium urecholine urispas urso vermox zyloprim acetylsalicylic acid advil, medipren celebrex flunarizine imitrex ketorolac maxalt ponstel tylenol ultram benadryl ditropan eldepryl requip sinemet trivastal advil, medipren arava colchicine decadron feldene indocin sr mobic naprosyn zyloprim betamethasone differin nizoral oxsoralen prograf retin-a xenical advil, medipren allyloestrenol clomid, serophene diflucan evista folic acid fosamax isoflavone nexium parlodel ponstel prevacid prilosec progesterone provera, cycrin rocaltrol tibolone generic loxitane generic name: loxapine hydrochloride ; qty and vasodilan.
We are developing a broad portfolio of drugs based on the novel biological finding that bacteria exposed to antibiotics in front-loaded, sequential bursts, or pulses, are killed more efficiently than those exposed to standard antibiotic treatment regimens.
Jun 20, 2007 aidsmap, during the first year of art, 636 74% ; received tb prophylaxis isoniazid or cotrimoxazole ; and 214 25% ; received tb therapy and ketorolac.
20.052.759 Etambutol, isoniazida, pirazinamida, rifampicina 3.531.471 Artesunato, mefloquina, pirimetamina sulfadoxina, primaquina, quinina.
200300mg daily.1 If the patient is receiving haemodialysis therapy, the dose should be given after the dialysis session, as it may be removed during dialysis.1 Pyridoxine therapy is recommended for prophylaxis of peripheral neuropathy associated with isoniazid. The usual dose is 10mg daily.1 However, some authors recommend that a dose of 100mg daily be given to haemodialysis patients due to a reported increased incidence of neurotoxic side-effects in such patients. These side effects are because of abnormal metabolism of pyridoxine and rapid clearance of the active metabolite.4 Pyrazinamide is excreted primarily by hepatic metabolism with only a small percentage being excreted unchanged in the urine. Dose reduction is not required in patients with renal impairment.1 It is possible that ciprofloxacin was included in the antitubercular regimen as an alternative to ethambutol due to suspected drug resistance. Ethambutol is also associated with an increased incidence of visual disturbances in patients with renal failure.2 The co-administration of quinolone antibiotics such as ciprofloxacin and calcium results in the formation of insoluble compounds in the gut. This interaction is clinically significant and may result in inadequate treatment of a potentially serious infection such as tuberculosis.5 Care must be taken to separate administration times by at least two hours.5 At Addenbrooke's, the calcium is usually and ketotifen.
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The two antibiotics most commonly used are rifampicin and isoniazid and lamictal.
Aesthetic physicians are becoming increasingly sophisticated in combining medications and medical devices to achieve optimal results and reduce side effects. Patients also feel they are taking a more active role in their therapy by choosing multiple modalities.
Tuberculosis is the world's leading cause of death from a single infectious organism. Standard tuberculosis chemotherapy consists of a lengthy treatment with at least two so-called first-line drugs, e.g. isoniazid and rifampicin. Unfortunately, an increasing number of tuberculosis cases are encountered that cannot be treated because of resistance to one or more of these drugs 1, 2 ; . The last resort for combating such multi ; drug-resistant mycobacterial infections relies mainly on the action of second-line antitubercular drugs. For this reason, several thioamide drugs have been successfully employed during the last decades Fig. 1 ; . However, as for other antitubercular agents, more and more infections are encountered that are also resistant to thioamide-based treatment. Despite their widespread use, the mode of action of thioamide antibiotics as and lamotrigine.
Twenty studies were identified through the combined search strategies as eligible for inclusion in the study. All reports had been published, although two studies had not been published in full.16 26 The full report of one trial was provided by the author in the form of an unpublished manuscript, 16 and a detailed report of the other was obtained from conference proceedings.26 Four studies had been reported in more than one publication.16 2628 One further randomised controlled trial of patients who deliberately harmed themselves was identified, but this did not include repetition of deliberate self harm as an outcome variable.29 We were unable to obtain this information from the authors of this trial. The trials identified were grouped as described in the methods section. Table 1 summarises the 20 trials included in the review, their groupings, details of participants sex and the proportion with a history of self harm--"repeaters" ; , the interventions used, and the quality of concealment scores. Only one trial was specifically of adolescents.22 The assessment of quality of concealment of allocation table 1 ; resulted in 13 trials being given a score of 3 for adequate concealment ; , three trials being given a score of 2 unclear concealment ; , and four trials being given a score of 1 inadequate concealment ; . Blinding of assessors was not stated or, for example, synthesis of isoniazid.
Generally all of the states have the following high-level educational focus as directed by the central government: Wired schools are being promoted Computer literacy is a focus New schools and universities are being opened Computer education is becoming compulsory at various class levels. The number of available seats at technical institutions and in training programs is being increased. In addition, the individual states are setting up their own Indian Institutes of Information Technology, partnering with multi-national corporations to provide additional training, upgrading their training facilities to support the IT Enabled Services sector, creating software technology and hardware parks. The following are some specific examples of regional IT initiatives that impact skill gaps. Kerala Kerela's State Institute of Educational Technology SIET ; Project is responsible for the planning, research, production and evaluation of education software. It has plans to develop an Education Communication Floor equipped with all available audio-visual devices and demonstrations of education gadgets. This lab will provide teachers and students with hands-on experiences on computer multimedia. Delhi Delhi's Taskforce for Formulating Information Technology Policy identified that Delhi has the potential for providing IT Enabled Services at economical costs and is a destination for software and hardware companies. "Delhi" 2003 ; Madhya Pradesh The vision statement in Madhya Pradesh's report from The State Task Force on Information Technology indicates there should be no islands of elitism or conclaves of wisdom. Every citizen must feel comfortable in accessing and imparting information through the facility of technology. "Final Report" 2003 ; Madhya Pradesh's goal is to contribute at least 5 to 10% of the IT output of India by the year 2008 and to create employment opportunities for 1 million people in IT-related activities. To accomplish this goal the state must attract investors. They will accomplish this by providing cost effective infrastructure in addition to transparent and responsive governance. In addition they must provide information access to all citizens and achieve IT literacy in all high schools and colleges by the year 2003 and all schools by 2008. Similar to the National IT Task Force's recommendations, Madhya Pradesh proposes permitting the use of computers after office hours by employees in IT courses and providing suitable floor and levothyroxine.
Mycobacterium tuberculosis MTB ; test: Respiratory specimen Prepration kit Mycobacterium Amplification kit Mycobacterium detection kit Mycobacterium tuberculosis positive kit Mycobacterium tuberculosis negative kit INH - strip Isoniazid strip ; Analutor software -5 M.B redox for sensitivity detection of mycobacterium M.B redox for sensitivity of mycobacterium XYL Xylene ; 2 x 5ml CLO test vial Elisa test for Mycoplasma pneumonia Ag vial WRZC 3480W Sal. O- agg. Serum 2ml vial Aspergillosis immunodlffusion 1D ; kit Blastomycosis latex agglotination LA ; kit Candidiasis latex agglotionate LA ; kit 76 of 151.
One of the great benefits of heart surgery is being able to do more. Taking exercise will: Make you feel good. Help your heart recover. Help you sleep better. Build up your fitness. Lower your blood pressure. Help you to maintain a healthy weight. Lower your cholesterol levels. Help your heart stay well and give you energy for life and lithobid.
In 2001, all 44 isolates from culture confirmed cases of both pulmonary and nonpulmonary tuberculosis cases were examined for susceptibility to anti-tuberculous drugs. Forty-two of these isolates were identified as M. tuberculosis 27 pulmonary and 15 non-pulmonary ; and the remaining 2 isolates were identified as M. bovis 1 pulmonary and 1 non-pulmonary ; . Of the 42 M. tuberculosis isolates, two were found resistant to isoniazid only and a further was found resistant to pyrazinamide only. Each of the M. bovis isolates was found resistant to pyrazinamide only.
Because rifater contains both rifampin and isoniazid, it should only be given with caution and under strict medical supervision to patients with impaired liver function and lithium!
He consequences of high-risk alcohol use by students continue to be the greatest health and safety problem facing colleges and universities in the U.S. These effects range from academic problems to vandalism, injury, assaults, and deaths. These effects are of a magnitude which far outweighs any other threat to health and safety on campus and perhaps all other such concerns combined. Recent data from the CORE Institute would indicate that the problem may be worsening, with heavy drinking, defined as five or more drinks in one sitting, having increased to 55.6% of students in 2005, up from 49.8% in 2003 and 46.5% in 2000.1, 2, 3 Despite this national trend, many individual campuses have seen significant improvements. However, despite good data on effective approaches to reducing consumption and the problems associated with excessive alcohol use, many campuses continue to focus their limited prevention resources on programs that are not likely to produce the desired change; still investing in programs that aim simply to provide information to students about the ills of alcohol use, through brochures, posters, speakers, workshops, and skits, for example. Also, alcohol prevention efforts are often evaluated on workshop attendance, whether students enjoy a speaker, or even the number of brochures distributed. Any discussion of evidence-based approaches to alcohol problem prevention on campus operates from the assumption that behavior change decreased consumption and even more importantly, the resulting changes in individuals and the environment fewer adverse consequences to individual drinkers, other students, campus property, and the neighborhoods surrounding campuses are the measures of an "effective" approach. This article outlines the state of our knowledge of effective approaches to combating excessive alcohol use on campus and suggests key resources campuses can turn to for guidance in planning and implementing an evidence-based approach. Several leading researchers.
When isoniazid is used to treat active tb, it is used in combination with another tuberculosis drug in order to prevent resistant strains and loxitane and isoniazid.
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For additional information on managing isoniazid poisoning, see the October 1995 issue of Veterinary & Human Toxicology which has an in-depth review of the pathophysiology and treatment of acute isoniazid poisoning in dogs. To learn more about instances of tuberculosis in New Yorkers see nyc.gov.
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Case of epithelial ovarian cancer, as an exhaustive literature search revealed only one similar report4. CASE REPORT A 61-year-old lady presented with ascites and progressive abdominal distension of 3 months duration. She had no past medical illnesses. Two months prior to presentation she developed tremors of hands, bradykinesia, dysphagia and hypophonia. These symptoms progressed rapidly and soon she became bedridden. Subsequently, she received one month of empirical antitubercular treatment with Isoniazid, Rifampicin, Pyrazinamide, Streptomycin and Ethambutol, along with Frusemide and Spironolactone. There was no history of dementia. Examination revealed a normotensive elderly lady with pitting edema of the feet and mild dehydration .She had marked ascites with palpable abdominal masses. Neurological examination showed intact higher mental functions and cranial nerves. Jaw jerk was not brisk. She had evidence of severe Parkinsonian features including mask-like face, tremors at rest in extremities, cogwheel rigidity, and extreme bradykinesia. Motor power and sensations in the limbs were intact. Initial investigations revealed serum sodium 113 meq L, potassium 2.3 meq L, serum albumin 2.7 mg dl, CA- 125 of14053.0 u ml. The CBC, other liver function tests, and renal function tests were normal. CT scan of the abdomen revealed multiple peritoneal deposits, omental caking, and matted bowel loops. Ascitic fluid and loxapine.
GENERIC DRUG Propranol 20mg Tablet Propranol 40mg Tablet Propranol 80mg Tablet Indometnhacin 25mg Capsule Atropine Sulfate 1% Ophthalmic Solution Pilocarpine 1% Op Solution Pilocarpine 2% Op Solution Potassium Chl 10Meq Cr Tablet Potassium Chl 10Meq Tablet Potassium Chloride 20Meq 15 Liquid Triamcinolone .1 Cr 30Gm Cephalexin 250mg Capsule Cephalexin 500mg Capsule Cephalexin 125mg 5ml Suspension Cephalexin 250mg 5ml Suspension Cephalexin 125mg 5ml Suspension Cephalexin 250mg 5ml Suspension Digitek 0.125mg Tablet Digitek 0.25mg Tablet Furosemide 20mg Tablet Furosemide 40mg Tablet Furosemide 80mg Tablet Hyoscyamine 0.375mg Er Tablet Hyoscyamine 0.125 ml Drop Hyoscyamine 0.125mg Sublingual Tablet Hyoscyamine 0.125mg Tablet Fluocinonide 0.05% Cream Fluocinonide 0.05% Cream Baclofen 10mg Tablet Metoprolol 25mg Tablet Metoprolol 50mg Tablet Metoprolol 100mg Tablet Benazepril 10mg Tablet Benazepril 20mg Tablet Benazepril 5mg Tablet Benazepril 40mg Tablet Indapamide 2.5mg Tablet Indapamide 1.25mg Tablet Sod Fluroide 0.25mg Chewable Magnesium Oxide 400mg Tablet BRAND NAME * Inderal Inderal Inderal Indocin Isopto Atropine Isopto Carpine Isopto Carpine K-Dur K-Tab Kay-Ciel Kenalog Keflex Keflex Keflex Keflex Keflex Keflex Lanoxin Lanoxin Lasix Lasix Lasix Levbid Levsin Levsin Levsin Lidex Lidex Lioresal Lopressor Lopressor Lopressor Lotensin Lotensin Lotensin Lotensin Lozol Lozol Luride Mag-Ox QTY 60 GENERIC DRUG Neo Poly Dex 0.1% Ophthalmic Ointment Neo Poly Dex 0.1% Ophthalmic Suspension Triamt Hctz 37.5 25 Tablet Triamt Hctz 75 50mg Tablet Methylprednisolone 4mg Dosepak Methylprednisolone 4mg Tablet Megestrol 20mg Tablet Thioridazine 25mg Tablet Thioridazine 50mg Tablet Lovastatin 10mg Tablet Glyburide 2.5mg Tablet Hydrochlorothiazide 12.5mg Capsule Prazosin 1mg Capsule Prazosin 5mg Capsule Prazosin 2mg Capsule Meloxicam 15mg Tablet Meloxicam 7.5mg Tablet Amiloride Hctz 5mg 50mg Tablet Ibuprofen 800mg Tablet Ibuprofen 600mg Tablet Ibuprofen 400mg Tablet Ibuprofen 100mg 5ml Suspension Nystatin-Triamcin Cream Nystatin-Triamcin Ointment Naproxen 375mg Tablet Naproxen 500mg Tablet Prenatal Rx Bad Tablet Thiothixene 2mg Capsule Natalcare Pic Tablet Nystatin 100000U Cream Nystatin 100000U Ointment Nystatin 100000U Cream Isoniazid 300mg Tablet Estropipate 0.625mg Tablet Estropipate 1.25mg Tablet Nortriptylin 25mg Capsule Nortriptylin 10mg Capsule Paroxetine 10mg Tablet Paroxetine 20mg Tablet BRAND NAME * Maxitrol Maxitrol Maxzide Maxzide Medrol Medrol Megace Mellaril Mellaril Mevacor Micronase Microzide Minipress Minipress Minipress Mobic Mobic Moduretic Motrin Motrin Motrin Motrin Mycolog Ii Mycolog Naprosyn Naprosyn Natalins Navane Niferex-Pn Nilstat Nilstat Nilstat Nydrazid Ogen Ogen Pamelor Pamelor Paxil Paxil QTY 4 10 30 Page.
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43 Drug Abuse Control 513.10 HYPODERMIC POSSESSION, DISPLAY AND DISPENSING. A ; Possession of a hypodermic is authorized for: 1 ; Any manufacturer or distributor of, or dealer in, hypodermics or medication packaged in hypodermics, and any authorized agent or employee of such manufacturer, distributor or dealer, in the regular course of business. 2 ; A hospital, owner of a pharmacy or pharmacist in the regular course of business. 3 ; Any practitioner, nurse or other person authorized to administer injections, in the regular course of his profession or employment. 4 ; Any person, when the hypodermic in his possession was lawfully obtained and is kept and used for the purpose of self-administration of insulin or other drug prescribed by a practitioner for the treatment of disease. 5 ; Any person whose use of a hypodermic is for legal research, clinical or medicinal purposes. 6 ; Any farmer, for the lawful administration of a drug to an animal. 7 ; Any person whose use of a hypodermic is for lawful professional, mechanical, trade or craft purposes. B ; No manufacturer or distributor of, or dealer in, hypodermics or medication packaged in hypodermics, or their authorized agents or employees, and no owner of a pharmacy, or pharmacist, shall display any hypodermic for sale. No person authorized to possess a hypodermic pursuant to Subsection a ; hereof shall negligently fail to take reasonable precautions to prevent any hypodermic in his possession from theft or acquisition by any unauthorized person, or negligently discard a hypodermic without first having rendered it completely unusable for its original purpose. C ; A pharmacist or person under the direct supervision of a pharmacist may furnish hypodermics to another without a prescription by a practitioner, but the pharmacist or person under his supervision shall require positive identification of each person to whom hypodermics are furnished, and shall keep a written record of each transaction, including the date, the type and quantity of the articles furnished, and the name, address and signature of the person to whom such articles are furnished. Such record shall be retained in the same manner as the exempt narcotics register. No pharmacist or person under his supervision shall fail to comply with this Subsection c ; in furnishing hypodermics. ORC 3719.172.
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Cimetidine salvage of isoniazid-rifampicin hepatotoxicity signed rank test; p values 0.05 Food intake Liver weight Animals with changes in liver n ; were taken as g ; g ; Inflammation Necrosis significant. 90 5.5 ; 24.67 2.66 ; 0 0 a 2.0 ; 24.50 3.39 ; 2 0 Results.
Hour period for the preceding 48 hours or longer. 3. In patients with conditions purported to increase susceptibility to acetaminophen toxicity alcoholism, isoniazid use, prolonged fasting ; , the dose of acetaminophen considered as RSTI should be greater than 4 g or 100 mg kg whichever is less ; per day Grade D ; . 4. Gastrointestinal decontamination is not needed Grade D and vasodilan.
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